Occupational asthma caused by dry metabisulphite.

نویسندگان

  • J L Malo
  • A Cartier
  • A Desjardins
چکیده

A case is described of occupational asthma in a worker with no previous history of asthma who sprinkled dried metabisulphite powder onto potatoes and developed work-related symptoms. Occupational asthma was confirmed by specific inhalation challenges.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

CASE STUDY Metabisulphite-induced occupational asthma in a radiographer

There is epidemiological evidence for an increased prevalence of occupational asthma among radiographers. However, the causes of darkroom disease are not yet defined. A 37-year-old female radiographer reported work-related asthma ,2 yrs after starting work in a local hospital. She was atopic and showed bronchial hyperresponsiveness to methacholine. Occupational-type exposure with a fixing agent...

متن کامل

Inhibition of sodium metabisulphite induced bronchoconstriction by frusemide in asthma: role of cyclooxygenase products.

BACKGROUND Inhaled frusemide inhibits airway responses to sodium metabisulphite and other indirect bronchial challenges in asthma by undetermined mechanisms which may relate to its ability to stimulate prostaglandin release. Inhalation of sodium metabisulphite provokes indirect bronchoconstriction, possibly by activating sensory nerves. To investigate the role of cyclooxygenase products in the ...

متن کامل

Cross refractoriness between sodium metabisulphite and exercise induced asthma.

BACKGROUND Exercise and inhaled sodium metabisulphite are thought to cause bronchoconstriction in asthma through different mechanisms. The response to both stimuli becomes refractory with repeat challenge. The mechanism of refractoriness is unclear, although depletion of mast cell derived mediators or neurotransmitters has been suggested. Recent studies suggest a common mechanism involving rele...

متن کامل

Refractoriness to inhaled sodium metabisulphite in subjects with mild asthma.

Refractoriness occurs after challenges causing mediator release in asthma, by a mechanism which may involve inhibitory prostaglandins. Bronchoconstriction due to inhaled sodium metabisulphite is thought to involve neural pathways and to be independent of mediator release; whether it shows refractoriness is uncertain. We have sought evidence of refractoriness to the bronchoconstrictor response t...

متن کامل

The effect of amiloride on the airway response to metabisulphite in asthma: a negative report.

Frusemide, a loop diuretic, has been shown to potently inhibit several indirect bronchoconstrictor challenges in asthma. The mechanism by which nebulized frusemide protects against indirect bronchoconstrictor stimuli in asthma is not known. One mechanism could be related to inhibition of sodium transport. If this is the case, then amiloride, another inhibitor of sodium transport, should also pr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Thorax

دوره 50 5  شماره 

صفحات  -

تاریخ انتشار 1995